Lhermitte’s sign in MS: Causes, triggers, and treatment

Some people prefer to call Lhermitte’s sign, the barber chair phenomenon because it may happen when the head is bent forward rapidly. People have likened the sensation, which is due to stimulation of irritated nerves or the spinal cord, to hitting the elbow or “funny bone.”

The most common triggers of Lhermitte’s sign include:

  • bending the neck so that the chin touches the chest
  • fatigue
  • stress
  • overheating

In this article, we examine the causes of Lhermitte’s sign and how it relates to multiple sclerosis or MS. We also take a look at the treatment options and when someone should see a doctor about this symptom.

Causes of Lhermitte’s sign

Lhermitte’s sign tends to occur most often in people with MS. MS is a disease that mistakenly attacks the central nervous system (CNS). The CNS comprises the brain and spinal cord.

MS damages the myelin sheath, the protective, insulating material that coats the nerve fibers in the brain and spinal cord.

This damage interrupts the flow of signals across parts of the CNS, which can result in a range of sensory and motor symptoms.

The two main causes of Lhermitte’s sign are:

  • demyelination, which is where damage to the myelin around the nerves occurs
  • hyperexcitability, or increased firing of nerve fibers in the brain

Miscommunication between damaged nerve fibers can also cause Lhermitte’s sign.

Lhermitte’s sign is present in other demyelinating disorders, such as neuromyelitis optica that affects the optic nerve and spinal cord.

Doctors also associate Lhermitte’s sign with other medical conditions that affect the spinal cord in the neck region. These include:

  • Behcet’s disease, a rare autoimmune disorder causing inflammation in blood vessels in the body.
  • Arnold-Chiari malformation, where the base of the skull is too small, forcing part of the brain down through the skull and into the upper spinal column.
  • Myelopathy, which results from inflammation or injury to the spinal cord.
  • Spondylosis, which is a degenerative condition affecting the spinal cord.
  • Cervical disc herniation, which affects the spine.
  • Spinal cord tumors.
  • Spinal cord injury.
  • Vitamin B-12 deficiency.
  • Some radiation or chemotherapy treatments for cancer.

Vitamin B-12 deficiency can cause Lhermitte’s sign, as vitamin B-12 is necessary for the production and maintenance of myelin. Myelin is the fatty substance that makes up the myelin sheath and covers nerve fibers.

In one study of 114 people with MS, researchers found that a third of the participants experienced Lhermitte’s sign. Around 16 percent of these people had the symptom during their first episode of MS.


Fatigue, stress, and heat can all trigger Lhermitte’s sign, in addition to certain neck movements. These aspects may also trigger other MS symptoms in people with the condition.

Relaxation techniques, such as meditation or massage, deep breathing, and stretching exercises, may be useful in pain management.

Wearing a soft neck brace may also help a person avoid making neck movements that trigger Lhermitte’s sign.

Electrical stimulating devices, such as transcutaneous electrical nerve stimulation units, use a mild electric current to ease pain. These electrical pulses help reduce the pain signals and relax the muscles.

They may also lead to the production of hormones called endorphins that act as natural painkillers.

A doctor may prescribe a drug to treat nerve pain. Possible drugs include:

  • amitriptyline
  • duloxetine
  • gabapentin
  • pregabalin

These medications can all help with Lhermitte’s sign in people with MS.


Lhermitte’s sign can be bothersome, frustrating, and sometimes frightening. Despite this, it is important to note that Lhermitte’s sign is not life-threatening.

This symptom does not indicate disease progression in people with demyelinating disorders such as MS.

If a person with MS experiences an unexpected electric shock-like sensation down their neck and spine after bending or flexing their neck, they should speak to a doctor immediately.

Treatment options are available to manage Lhermitte’s sign and other MS symptoms. These treatments focus on changing a person’s behavior and lifestyle habits to minimize pain and stress and maximize quality of life.

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